GWAS-ROCS Database: Showing GR-Card for GR00579: Alzheimer's disease

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Record Information

Version

1.0

Creation Date

2019-12-09 18:09:32 UTC

Last Updated

2020-04-15 17:38:10 UTC

GWAS-ROCS ID

GR00579

Study Information

Condition/Phenotype

Alzheimer's disease

GWAS Central Data Set ID

Not Available

PubMed ID

30820047

Meta-Analysis (Yes/No)

Yes

Control Subjects

59163

Case Subjects

35274

SNPs

Name	Odds Ratio	Allele Frequency	p-value
rs429358	3.32	0.216	3.0e-64
rs6733839	1.2	0.407	2.1e-44
rs3851179	0.88	0.356	6.0e-25
rs4844610	1.17	0.187	3.6e-24
rs9331896	0.88	0.387	4.6e-24
rs7933202	0.89	0.391	1.9e-19
rs3752246	1.15	0.182	3.1e-16
rs75932628	2.08	0.008	2.7e-15
rs73223431	1.1	0.367	6.3e-14
rs3740688	0.92	0.448	5.4e-13
rs11218343	0.8	0.04	2.9e-12
rs9271058	1.1	0.27	1.4e-11
rs9473117	1.09	0.28	1.2e-10
rs10808026	0.9	0.199	1.3e-10
rs12539172	0.92	0.303	9.3e-10
rs17125924	1.14	0.093	1.4e-09
rs7920721	1.08	0.389	2.3e-09
rs10933431	0.91	0.223	3.4e-09
rs12881735	0.92	0.221	7.4e-09
rs138190086	1.32	0.02	7.5e-09
rs6024870	0.88	0.088	3.5e-08

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Simulated Population

ROC Plot

AUROC

0.663009

Logistic Regression Equation

log(p/(1 - p)) = 0.746 - 0.599(rs4844610) + 17.157(rs6733839) - 0.057(rs10933431) + 17.730(rs9271058) - 0.914(rs75932628) + 0.066(rs9473117) + 0.296(rs12539172) - 0.207(rs10808026) + 0.016(rs73223431) - 0.720(rs9331896) + 0.029(rs3740688) + 0.813(rs7933202) - 0.381(rs3851179) - 0.171(rs11218343) + 0.053(rs17125924) + 0.256(rs12881735) + 0.514(rs3752246) - 35.843(rs429358) + 0.081(rs6024870) + 0.242(rs7920721) + 0.295(rs138190086)

Heritability

0.106

Regression Type

OLS

Download File

GR00579.csv