The GWAS-ROCS Database is a freely available electronic database containing the largest and most comprehensive set of SNP-derived AUROCs. All of the data is either directly from, or derived from, studies accessible through PubMed or GWAS Central — an open-access online repository of summary-level genome-wide association study (GWAS) data. The database currently houses 579 simulated populations (corresponding to 219 different conditions) and SNP data (odds ratio, risk allele frequency, and p-values) for 2886 unique SNPs. Each study simulation record (GR-Card) contains information detailing the original study as well as simulated population data (e.g. ROC curves, AUROCs, SNP-heritability scores) determined from careful population modelling to recreate individual-level GWAS data. All GWAS-ROCS data is downloadable and is intended for applications in genomics, biomarker discovery, and general education.
Citing the GWAS-ROCS Database
The GWAS-ROCS Database is offered to the public as a freely available resource. Use and re-distribution of the data, in whole or in part, for commercial purposes requires explicit permission of the authors and explicit acknowledgment of the source material (GWAS-ROCS Database) and the original publication (see below). We ask that users who download significant portions of the database cite the following paper in any resulting publications.
- Patron J, Serra-Cayuela A, Han B, Li C, Wishart DS, Assessing the performance of genome-wide association studies for predicting disease risk. PLoS One. 2019 Dec 5;14(12):e0220215. 31805043