Showing GR-Card for GR00548: Type 2 diabetes (HGVRS5628)

Record Information
Version1.0
Creation Date2019-04-04 18:01:18 UTC
Last Updated2020-04-06 20:49:15 UTC
GWAS-ROCS IDGR00548
Study Information
Condition/PhenotypeType 2 diabetes
GWAS Central Data Set IDHGVRS5628
PubMed ID24509480
Meta-Analysis (Yes/No)No
Control Subjects139611
Case Subjects47979
SNPs
NameOdds RatioAllele Frequencyp-value
rs79031461.40.38.0e-75
rs108116611.180.821.0e-27
rs77569921.20.262.0e-26
rs11118751.150.583.0e-19
rs38021771.160.72.0e-18
rs44029601.130.311.0e-17
rs1631841.090.52.0e-14
rs99363851.130.391.0e-12
rs71785721.080.72.0e-11
rs52151.080.383.0e-11
rs125717511.090.512.0e-10
rs18012821.160.886.0e-10
rs44307961.130.539.0e-10
rs44585231.090.592.0e-09
rs8491351.120.522.0e-09
rs112576551.060.233.0e-09
rs76124631.10.877.0e-09
rs29436401.090.637.0e-09
rs117171951.090.782.0e-08
rs129701341.080.273.0e-08
rs177915131.210.933.0e-08
rs22611811.160.094.0e-08
rs48128291.070.165.0e-08
rs78452191.080.536.0e-08
rs15522241.130.831.0e-07
rs108309631.110.272.0e-07
rs5169461.10.772.0e-07
rs171684861.130.193.0e-07
rs20282991.040.295.0e-07
rs128998111.090.36.0e-07
rs20754231.080.662.0e-06
rs27964411.070.632.0e-06
rs39231131.040.612.0e-06
rs2430881.090.463.0e-06
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Simulated Population
ROC PlotGr00548
AUROC0.639432
Logistic Regression Equationlog(p/(1 - p)) = 1.554 - 2.412(rs7903146) - 0.172(rs10811661) - 3.250(rs7756992) - 15.203(rs1111875) - 16.943(rs3802177) - 0.795(rs4402960) + 0.421(rs163184) - 0.810(rs9936385) + 16.706(rs7178572) + 0.892(rs5215) + 0.382(rs12571751) - 0.002(rs1801282) - 0.428(rs4430796) + 14.774(rs4458523) - 0.279(rs849135) + 0.273(rs11257655) + 0.236(rs7612463) - 16.408(rs2943640) + 0.402(rs11717195) + 16.434(rs12970134) - 0.484(rs17791513) - 0.170(rs2261181) + 0.162(rs4812829) + 0.261(rs7845219) - 0.237(rs1552224) - 16.589(rs10830963) - 0.021(rs516946) - 0.327(rs17168486) + 5.060(rs2028299) + 0.655(rs12899811) - 0.147(rs2075423) + 16.656(rs2796441) + 0.417(rs3923113) + 0.106(rs243088)
Heritability0.078
Regression TypeOLS
Download FileGR00548.csv