Showing GR-Card for GR00509: Systemic sclerosis (HGVRS1541)

Record Information
Version1.0
Creation Date2019-04-04 18:01:17 UTC
Last Updated2020-04-06 20:49:15 UTC
GWAS-ROCS IDGR00509
Study Information
Condition/PhenotypeSystemic sclerosis
GWAS Central Data Set IDHGVRS1541
PubMed ID21750679
Meta-Analysis (Yes/No)No
Control Subjects5702
Case Subjects2246
SNPs
NameOdds RatioAllele Frequencyp-value
rs64576171.610.52.0e-37
rs75748651.380.222.0e-13
rs31305731.250.326.0e-10
rs22332871.310.15.0e-09
rs104886311.350.094.0e-07
rs20566261.20.611.0e-06
rs130214011.210.233.0e-06
Simulated Population
ROC PlotGr00509
AUROC0.593915
Logistic Regression Equationlog(p/(1 - p)) = 1.411 - 0.610(rs6457617) - 0.595(rs7574865) + 0.066(rs3130573) + 0.039(rs2233287) - 0.115(rs10488631) - 0.050(rs2056626) + 0.128(rs13021401)
Heritability0.035
Regression TypeOLS
Download FileGR00509.csv