Showing GR-Card for GR00506: Systemic lupus erythematosus (HGVRS6358)

Record Information
Version1.0
Creation Date2019-04-04 18:01:17 UTC
Last Updated2020-04-06 20:49:15 UTC
GWAS-ROCS IDGR00506
Study Information
Condition/PhenotypeSystemic lupus erythematosus
GWAS Central Data Set IDHGVRS6358
PubMed ID26606652
Meta-Analysis (Yes/No)No
Control Subjects2317
Case Subjects1393
SNPs
NameOdds RatioAllele Frequencyp-value
rs125397412.110.2226.0e-31
rs47281421.760.3871.0e-23
rs11436792.30.0713.0e-21
rs10597021.724140.58.0e-14
rs118893411.50.4077.0e-13
rs77083921.760.4992.0e-11
rs127361951.515150.7217.0e-11
rs49173851.388890.6481.0e-08
rs133065751.620.1053.0e-08
rs18781861.820.0471.0e-07
rs6439551.490.7484.0e-07
rs112318241.510.1117.0e-07
rs29284021.390.1821.0e-06
rs100329092.420.0131.0e-06
rs1815022284.350.0122.0e-06
rs617324913.360.0062.0e-06
rs78925861.369860.7123.0e-06
rs1900290112.857140.9773.0e-06
rs70981872.620.0093.0e-06
rs27977801.370.1675.0e-06
rs81054291.290.3925.0e-06
rs45746841.340.2087.0e-06
rs178076241.310.647.0e-06
rs9311271.330.7037.0e-06
rs70313251.450.5127.0e-06
rs38622601.428570.5667.0e-06
rs3300481.410.7667.0e-06
rs173010131.428570.5838.0e-06
rs102542841.290.5838.0e-06
rs46411211.470590.8518.0e-06
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Simulated Population
ROC PlotGr00506
AUROC0.692047
Logistic Regression Equationlog(p/(1 - p)) = 2.458 - 1.986(rs12539741) - 0.314(rs4728142) - 1.718(rs1143679) + 14.526(rs1059702) - 1.240(rs11889341) - 16.020(rs7708392) - 1.498(rs12736195) - 0.231(rs4917385) + 1.175(rs13306575) + 0.913(rs1878186) - 2.130(rs643955) - 0.376(rs11231824) + 1.095(rs2928402) + 0.263(rs10032909) - 1.628(rs181502228) + 0.001(rs61732491) + 1.793(rs7892586) - 1.298(rs190029011) + 1.170(rs7098187) + 0.656(rs2797780) + 2.039(rs8105429) + 0.055(rs4574684) - 0.239(rs17807624) + 0.190(rs931127) - 0.292(rs7031325) + 1.172(rs3862260) + 1.684(rs330048) + 0.118(rs17301013) + 0.193(rs10254284) + 0.052(rs4641121)
Heritability0.148
Regression TypeOLS
Download FileGR00506.csv