Showing GR-Card for GR00505: Systemic lupus erythematosus (HGVRS6074)

Record Information
Version1.0
Creation Date2019-04-04 18:01:17 UTC
Last Updated2020-04-06 20:49:15 UTC
GWAS-ROCS IDGR00505
Study Information
Condition/PhenotypeSystemic lupus erythematosus
GWAS Central Data Set IDHGVRS6074
PubMed ID28714469
Meta-Analysis (Yes/No)No
Control Subjects15984
Case Subjects11590
SNPs
NameOdds RatioAllele Frequencyp-value
rs127068611.760.1184.0e-71
rs75826941.560.2284.0e-69
rs11436791.540.1073.0e-62
rs37573871.440.2468.0e-33
rs27363361.340.2466.0e-32
rs22059601.420.3141.0e-30
rs770000601.890.032.0e-29
rs360141291.50.0791.0e-24
rs66796771.410.1012.0e-23
rs347256111.282050.2925.0e-23
rs129287251.940.0997.0e-22
rs357890101.460.0725.0e-19
rs1120063291.234570.2681.0e-16
rs1316581.250.2011.0e-16
rs118893411.480.3556.0e-16
rs22998641.240.1996.0e-15
rs24316971.315790.4674.0e-14
rs23278321.220.2122.0e-13
rs96526011.190480.3256.0e-13
rs44267781.265820.4531.0e-12
rs31226051.230.1441.0e-11
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Simulated Population
ROC PlotGr00505
AUROC0.684037
Logistic Regression Equationlog(p/(1 - p)) = 0.592 - 17.053(rs12706861) - 2.814(rs7582694) + 0.467(rs1143679) + 1.051(rs3757387) - 1.121(rs2736336) - 1.034(rs2205960) - 0.447(rs77000060) - 0.615(rs36014129) + 18.155(rs6679677) + 1.136(rs34725611) - 35.415(rs12928725) + 0.482(rs35789010) + 0.989(rs112006329) - 1.109(rs131658) - 1.366(rs11889341) + 0.625(rs2299864) + 0.151(rs2431697) + 1.853(rs2327832) + 1.071(rs9652601) + 0.161(rs4426778) + 33.796(rs3122605)
Heritability0.135
Regression TypeOLS
Download FileGR00505.csv