Showing GR-Card for GR00462: Restless legs syndrome (HGVRS4568)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:14 UTC
GWAS-ROCS IDGR00462
Study Information
Condition/PhenotypeRestless legs syndrome
GWAS Central Data Set IDHGVRS4568
PubMed ID29029846
Meta-Analysis (Yes/No)No
Control Subjects382638
Case Subjects45896
SNPs
NameOdds RatioAllele Frequencyp-value
rs1138515541.920.072.0e-280
rs611922591.260.594.0e-202
rs455442311.204820.587.0e-133
rs8680361.190480.685.0e-69
rs120465031.136360.413.0e-63
rs18209891.136360.471.0e-58
rs18362291.111110.527.0e-42
rs359876571.111110.674.0e-38
rs102087121.09890.641.0e-34
rs3650321.130.272.0e-34
rs109529271.130.132.0e-34
rs9960641.220.063.0e-27
rs176363281.111110.83.0e-26
rs803191441.111110.763.0e-25
rs1116520041.162790.93.0e-16
rs124508951.080.214.0e-14
rs18484601.070.262.0e-13
rs3405611.060.23.0e-09
rs625357671.063830.683.0e-09
rs129623051.050.251.0e-07
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Simulated Population
ROC PlotGr00462
AUROC0.622913
Logistic Regression Equationlog(p/(1 - p)) = 2.373 - 1.833(rs113851554) - 0.677(rs61192259) - 0.776(rs45544231) - 1.134(rs868036) - 0.169(rs12046503) + 0.157(rs1820989) + 0.362(rs1836229) + 1.373(rs35987657) + 0.246(rs10208712) - 0.607(rs365032) + 1.207(rs10952927) + 0.160(rs996064) - 0.122(rs17636328) + 0.159(rs80319144) - 0.114(rs111652004) - 0.436(rs12450895) + 0.146(rs1848460) + 0.489(rs340561) + 0.289(rs62535767) + 0.750(rs12962305)
Heritability0.060
Regression TypeOLS
Download FileGR00462.csv