Showing GR-Card for GR00461: Restless legs syndrome (HGVRS1590)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:14 UTC
GWAS-ROCS IDGR00461
Study Information
Condition/PhenotypeRestless legs syndrome
GWAS Central Data Set IDHGVRS1590
PubMed ID21779176
Meta-Analysis (Yes/No)No
Control Subjects7280
Case Subjects4857
SNPs
NameOdds RatioAllele Frequencyp-value
rs23004781.680.243.0e-49
rs125938131.410.681.0e-22
rs93572711.470.768.0e-22
rs31047671.350.589.0e-19
rs67479721.230.449.0e-11
rs19751971.290.163.0e-10
Simulated Population
ROC PlotGr00461
AUROC0.598104
Logistic Regression Equationlog(p/(1 - p)) = 1.034 - 0.715(rs2300478) - 0.224(rs12593813) - 0.450(rs9357271) - 0.069(rs3104767) + 0.414(rs6747972) + 0.060(rs1975197)
Heritability0.038
Regression TypeOLS
Download FileGR00461.csv