Showing GR-Card for GR00449: Psoriasis (HGVRS6311)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00449
Study Information
Condition/PhenotypePsoriasis
GWAS Central Data Set IDHGVRS6311
PubMed ID25903422
Meta-Analysis (Yes/No)No
Control Subjects19517
Case Subjects15369
SNPs
NameOdds RatioAllele Frequencyp-value
rs77092121.380.6572.0e-30
rs177283381.60.0546.0e-20
rs37475171.30.2741.0e-18
rs48454591.270.6515.0e-17
rs49214931.230.6417.0e-13
rs20668071.40.9323515.0e-12
rs6431771.250.2739.0e-12
rs95339621.140.4068.0e-11
rs80169471.260.5552.0e-10
rs8426251.160.5562.0e-10
rs28536941.230.4955.0e-10
rs47950671.20.3516.0e-10
rs125640221.170.2752.0e-09
rs205411.140.795.0e-09
rs2409931.150.268761.0e-08
rs19907601.180.6141.0e-08
rs137081.550.0798392.0e-08
rs343947701.160.6433.0e-08
rs285123561.170.7994.0e-08
rs81282341.170.1974.0e-08
rs22953591.150.3448.0e-08
rs37306821.160.1892.0e-07
rs119223721.140.227952.0e-07
rs73529441.150.59112.0e-07
rs117953431.150.5854.0e-07
rs93047421.170.6436.0e-07
rs563640761.160.3136.0e-07
rs4170651.170.2588.0e-07
rs107946481.20.7471.0e-06
rs93055561.10.420121.0e-06
rs60568691.120.2941.0e-06
rs8920851.160.5662.0e-06
rs28475001.140.1353.0e-06
rs108142471.080.3854.0e-06
rs37992961.090.4196.0e-06
rs579961741.130.2497.0e-06
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Simulated Population
ROC PlotGr00449
AUROC0.656545
Logistic Regression Equationlog(p/(1 - p)) = 0.669 - 1.531(rs7709212) - 1.029(rs17728338) - 16.744(rs3747517) - 1.345(rs4845459) + 0.635(rs4921493) - 0.268(rs2066807) - 15.922(rs643177) - 1.281(rs9533962) - 1.284(rs8016947) - 0.142(rs842625) - 0.230(rs2853694) - 1.479(rs4795067) + 15.725(rs12564022) + 0.252(rs20541) + 0.709(rs240993) - 0.296(rs1990760) - 0.900(rs13708) + 16.905(rs34394770) + 0.039(rs28512356) - 0.266(rs8128234) - 0.144(rs2295359) + 0.182(rs3730682) + 0.032(rs11922372) + 0.187(rs7352944) + 1.482(rs11795343) - 15.541(rs9304742) + 0.133(rs56364076) - 0.326(rs417065) + 0.440(rs10794648) + 0.810(rs9305556) + 16.001(rs6056869) - 0.103(rs892085) + 0.605(rs2847500) + 1.874(rs10814247) + 0.423(rs3799296) + 0.542(rs57996174)
Heritability0.098
Regression TypeOLS
Download FileGR00449.csv