Showing GR-Card for GR00442: Prostate cancer (HGVRS5672)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00442
Study Information
Condition/PhenotypeProstate cancer
GWAS Central Data Set IDHGVRS5672
PubMed ID26034056
Meta-Analysis (Yes/No)No
Control Subjects13571
Case Subjects14159
SNPs
NameOdds RatioAllele Frequencyp-value
rs119862201.540.0994.0e-45
rs69832671.250.513.0e-27
rs775416212.040820.0222.0e-26
rs112637631.220.5195.0e-24
rs69835611.450.0356.0e-22
rs10163431.250.216.0e-21
rs109939941.210.4017.0e-21
rs3765923641.20.526.0e-20
rs46462841.180.2981.0e-19
rs108964491.20.525.0e-19
rs1424636031.180.4174.0e-16
rs75019391.170.64.0e-15
rs15122681.170.434.0e-15
rs26591241.180.8541.0e-13
rs100869081.170.712.0e-12
rs93645541.140.2796.0e-12
rs104865671.170.773.0e-11
rs78089351.170.7663.0e-11
rs80715581.140.4837.0e-11
rs169021041.180.145.0e-10
rs1160410372.670.00016.0e-10
rs37318271.130.5841.0e-09
rs57591671.130.5052.0e-09
rs18599621.130.482.0e-09
rs101874241.130.583.0e-09
rs27358391.170.856.0e-09
rs727258791.920.6673.0e-08
rs76796731.120.595.0e-08
rs108759431.120.297.0e-08
rs9027741.160.159.0e-08
rs116497431.140.816.0e-07
rs3393311.120.716.0e-07
rs132522981.110.712.0e-06
rs175996291.120.219.0e-06
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Simulated Population
ROC PlotGr00442
AUROC0.63985
Logistic Regression Equationlog(p/(1 - p)) = 0.207 - 0.520(rs11986220) - 16.976(rs6983267) - 1.522(rs77541621) - 16.189(rs11263763) + 1.143(rs6983561) - 16.481(rs1016343) - 0.597(rs10993994) + 32.126(rs376592364) - 0.850(rs4646284) + 0.001(rs10896449) + 0.492(rs142463603) - 0.730(rs7501939) - 0.168(rs1512268) - 0.370(rs2659124) - 0.775(rs10086908) + 0.201(rs9364554) + 2.787(rs10486567) - 0.175(rs7808935) + 0.058(rs8071558) - 0.561(rs16902104) - 0.920(rs116041037) - 0.163(rs3731827) + 0.138(rs5759167) + 0.677(rs1859962) + 0.340(rs10187424) + 0.288(rs2735839) - 18.920(rs72725879) + 1.056(rs7679673) + 1.046(rs10875943) + 0.517(rs902774) + 0.218(rs11649743) + 0.290(rs339331) + 16.261(rs13252298) + 16.422(rs17599629)
Heritability0.078
Regression TypeOLS
Download FileGR00442.csv