Showing GR-Card for GR00439: Prostate cancer (HGVRS3546)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00439
Study Information
Condition/PhenotypeProstate cancer
GWAS Central Data Set IDHGVRS3546
PubMed ID23535732
Meta-Analysis (Yes/No)No
Control Subjects31178
Case Subjects30747
SNPs
NameOdds RatioAllele Frequencyp-value
rs19334881.120.594.0e-18
rs60625091.120.74.0e-16
rs6842321.10.365.0e-15
rs80082701.120.822.0e-14
rs76116941.10.594.0e-13
rs18942921.10.525.0e-13
rs121551721.110.235.0e-13
rs42457391.10.752.0e-11
rs115688181.10.562.0e-11
rs12708841.070.497.0e-11
rs111359101.110.168.0e-11
rs24059421.140.792.0e-10
rs71415291.090.53.0e-10
rs38506991.10.715.0e-10
rs72419931.090.72.0e-09
rs116504941.150.082.0e-09
rs30967021.070.45.0e-09
rs37715701.120.155.0e-09
rs22736691.070.158.0e-09
rs12185821.060.452.0e-08
rs119022361.070.273.0e-08
rs24273451.060.634.0e-08
rs68698411.070.215.0e-08
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Simulated Population
ROC PlotGr00439
AUROC0.546772
Logistic Regression Equationlog(p/(1 - p)) = 0.180 - 13.730(rs1933488) - 0.558(rs6062509) - 0.216(rs684232) + 0.023(rs8008270) + 13.622(rs7611694) - 0.338(rs1894292) - 0.453(rs12155172) + 0.132(rs4245739) - 0.049(rs11568818) + 0.156(rs1270884) - 0.462(rs11135910) - 0.182(rs2405942) + 0.023(rs7141529) + 0.356(rs3850699) + 0.030(rs7241993) - 0.162(rs11650494) + 0.160(rs3096702) - 0.143(rs3771570) + 0.359(rs2273669) + 0.093(rs1218582) + 0.214(rs11902236) + 0.258(rs2427345) + 0.364(rs6869841)
Heritability0.009
Regression TypePenalized
Download FileGR00439.csv