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Showing GR-Card for GR00428: Progressive supranuclear palsy (HGVRS1599)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00428
Study Information
Condition/PhenotypeProgressive supranuclear palsy
GWAS Central Data Set IDHGVRS1599
PubMed ID21685912
Meta-Analysis (Yes/No)No
Control Subjects6847
Case Subjects2165
SNPs
NameOdds RatioAllele Frequencyp-value
rs80707235.110.232.0e-118
rs17682081.370.715.0e-17
rs122035921.480.196.0e-15
rs75719711.330.744.0e-13
rs14114781.270.584.0e-11
rs66877581.270.816.0e-08
rs115685631.470.957.0e-08
rs68525351.230.341.0e-07
rs21429911.30.173.0e-07
Simulated Population
ROC PlotGr00428
AUROC0.806983
Logistic Regression Equationlog(p/(1 - p)) = 2.565 - 4.685(rs8070723) - 0.233(rs1768208) + 1.017(rs12203592) - 0.004(rs7571971) + 2.799(rs1411478) + 0.074(rs6687758) - 1.206(rs11568563) - 0.021(rs6852535) + 0.600(rs2142991)
Heritability0.377
Regression TypeOLS
Download FileGR00428.csv