Showing GR-Card for GR00424: Primary biliary cholangitis (HGVRS5676)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00424
Study Information
Condition/PhenotypePrimary biliary cholangitis
GWAS Central Data Set IDHGVRS5676
PubMed ID28062665
Meta-Analysis (Yes/No)No
Control Subjects8017
Case Subjects1893
SNPs
NameOdds RatioAllele Frequencyp-value
rs49794621.60060.4638.0e-19
rs93032771.434250.3084898.0e-11
rs74049281.260.6324.0e-09
rs68979321.518760.195136.0e-09
rs49385341.350430.4476321.0e-08
rs2305341.336060.3252491.0e-07
rs22933701.338590.2885771.0e-06
rs6445871.546140.1157681.0e-06
Simulated Population
ROC PlotGr00424
AUROC0.607684
Logistic Regression Equationlog(p/(1 - p)) = 1.817 - 1.706(rs4979462) - 3.070(rs9303277) + 0.236(rs7404928) - 0.376(rs6897932) + 1.096(rs4938534) + 2.949(rs230534) - 0.095(rs2293370) - 0.320(rs644587)
Heritability0.046
Regression TypeOLS
Download FileGR00424.csv