Showing GR-Card for GR00422: Primary biliary cholangitis (HGVRS1497)

Record Information
Version1.0
Creation Date2019-04-04 18:01:16 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00422
Study Information
Condition/PhenotypePrimary biliary cholangitis
GWAS Central Data Set IDHGVRS1497
PubMed ID21399635
Meta-Analysis (Yes/No)No
Control Subjects12328
Case Subjects3394
SNPs
NameOdds RatioAllele Frequencyp-value
rs77744341.60.384.0e-34
rs171297891.520.189.0e-20
rs109314681.50.122.0e-19
rs125317111.580.119.0e-17
rs4854991.380.572.0e-16
rs121342791.340.22.0e-14
rs37455161.380.232.0e-13
rs80171611.220.43.0e-13
rs64215711.370.813.0e-12
rs129247291.290.683.0e-12
rs76650901.260.524.0e-12
rs8604131.30.721.0e-11
rs9112631.290.712.0e-11
rs22933701.350.83.0e-11
rs111174321.310.765.0e-11
rs5381471.230.612.0e-10
rs9684511.270.191.0e-09
rs18006931.220.42.0e-09
rs13720721.20.372.0e-08
rs69744911.250.174.0e-08
rs72084871.320.848.0e-07
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Simulated Population
ROC PlotGr00422
AUROC0.649846
Logistic Regression Equationlog(p/(1 - p)) = 1.662 - 2.729(rs7774434) - 4.825(rs17129789) - 0.492(rs10931468) - 0.938(rs12531711) - 0.536(rs485499) + 3.174(rs12134279) - 0.607(rs3745516) - 0.066(rs8017161) - 0.520(rs6421571) - 0.192(rs12924729) + 0.879(rs7665090) - 0.018(rs860413) + 0.293(rs911263) - 0.139(rs2293370) - 0.047(rs11117432) + 0.190(rs538147) + 0.583(rs968451) + 0.001(rs1800693) + 2.269(rs1372072) + 2.200(rs6974491) + 0.408(rs7208487)
Heritability0.090
Regression TypeOLS
Download FileGR00422.csv