Showing GR-Card for GR00414: Parkinson's disease (HGVRS6418)

Record Information
Version1.0
Creation Date2019-04-04 18:01:15 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00414
Study Information
Condition/PhenotypeParkinson's disease
GWAS Central Data Set IDHGVRS6418
PubMed ID25064009
Meta-Analysis (Yes/No)No
Control Subjects100833
Case Subjects19061
SNPs
NameOdds RatioAllele Frequencyp-value
rs3561821.320.3674.0e-73
rs176495531.30.7742.0e-48
rs343118661.270.1911.0e-43
rs357490111.8240.0171.0e-29
rs126374711.18760.8072.0e-21
rs14740551.2140.1281.0e-20
rs64305381.14290.579.0e-20
rs117246351.1260.5539.0e-18
rs8231181.1220.5592.0e-16
rs769047981.1550.1435.0e-14
rs15553991.11480.5327.0e-14
rs1178967351.6240.0144.0e-13
rs1993471.110.591.0e-12
rs92753261.210.9061.0e-12
rs142351.1030.3812.0e-12
rs110601801.1050.5586.0e-12
rs124564921.110.3078.0e-12
rs24147391.1130.7341.0e-11
rs3296481.1050.3541.0e-11
rs68121931.10.6363.0e-11
rs81180081.1110.6573.0e-11
rs111580261.110.6656.0e-11
rs107975761.1310.145.0e-10
rs5913231.090.7257.0e-08
rs37939471.07640.5574.0e-07
rs621206791.0970.3146.0e-07
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Simulated Population
ROC PlotGr00414
AUROC0.604225
Logistic Regression Equationlog(p/(1 - p)) = 1.977 - 16.981(rs356182) - 0.675(rs17649553) - 0.569(rs34311866) - 2.117(rs35749011) - 0.152(rs12637471) - 0.300(rs1474055) - 0.812(rs6430538) - 3.301(rs11724635) - 1.369(rs823118) + 0.141(rs76904798) - 0.237(rs1555399) + 0.981(rs117896735) + 0.462(rs199347) + 0.061(rs9275326) + 16.034(rs14235) + 3.262(rs11060180) + 0.191(rs12456492) + 0.196(rs2414739) + 0.748(rs329648) + 0.117(rs6812193) + 0.046(rs8118008) - 0.165(rs11158026) + 0.258(rs10797576) + 0.340(rs591323) + 2.102(rs3793947) + 0.050(rs62120679)
Heritability0.043
Regression TypeOLS
Download FileGR00414.csv