Showing GR-Card for GR00409: Parkinson's disease (HGVRS1606)

Record Information
Version1.0
Creation Date2019-04-04 18:01:15 UTC
Last Updated2020-04-06 20:49:13 UTC
GWAS-ROCS IDGR00409
Study Information
Condition/PhenotypeParkinson's disease
GWAS Central Data Set IDHGVRS1606
PubMed ID21738487
Meta-Analysis (Yes/No)No
Control Subjects29624
Case Subjects3426
SNPs
NameOdds RatioAllele Frequencyp-value
rs346375849.620.0022.0e-28
rs3562201.290.3752.0e-19
rs121852681.30.793.0e-14
rs105137891.250.83.0e-10
rs68121931.190.648.0e-10
rs65993891.310.0754.0e-08
rs118680351.180.696.0e-08
rs8231561.210.821.0e-07
rs41300471.160.312.0e-07
rs28233571.150.386.0e-07
Simulated Population
ROC PlotGr00409
AUROC0.580578
Logistic Regression Equationlog(p/(1 - p)) = 2.639 - 2.311(rs34637584) - 16.215(rs356220) - 0.451(rs12185268) - 0.355(rs10513789) - 0.171(rs6812193) - 0.158(rs6599389) + 0.223(rs11868035) + 0.283(rs823156) + 0.008(rs4130047) + 16.106(rs2823357)
Heritability0.026
Regression TypeOLS
Download FileGR00409.csv