Showing GR-Card for GR00378: Ossification of the posterior longitudinal ligament of the spine (HGVRS4834)

Record Information
Version1.0
Creation Date2019-04-04 18:01:15 UTC
Last Updated2020-04-06 20:49:12 UTC
GWAS-ROCS IDGR00378
Study Information
Condition/PhenotypeOssification of the posterior longitudinal ligament of the spine
GWAS Central Data Set IDHGVRS4834
PubMed ID25064007
Meta-Analysis (Yes/No)No
Control Subjects13279
Case Subjects1660
SNPs
NameOdds RatioAllele Frequencyp-value
rs24232941.410.1551.0e-13
rs3748101.340.6112.0e-13
rs19796791.30.3624.0e-12
rs110450001.280.463.0e-11
rs132797991.280.3191.0e-10
rs9274851.330.1379.0e-09
Simulated Population
ROC PlotGr00378
AUROC0.57643
Logistic Regression Equationlog(p/(1 - p)) = 2.324 - 0.294(rs2423294) - 0.182(rs374810) - 0.199(rs1979679) - 0.047(rs11045000) + 0.108(rs13279799) + 0.102(rs927485)
Heritability0.023
Regression TypeOLS
Download FileGR00378.csv