Showing GR-Card for GR00375: Nonsyndromic cleft lip with or without cleft palate (HGVRS765)

Record Information
Version1.0
Creation Date2019-04-04 18:01:15 UTC
Last Updated2020-04-06 20:49:12 UTC
GWAS-ROCS IDGR00375
Study Information
Condition/PhenotypeNonsyndromic cleft lip with or without cleft palate
GWAS Central Data Set IDHGVRS765
PubMed ID20023658
Meta-Analysis (Yes/No)No
Control Subjects1318
Case Subjects1138
SNPs
NameOdds RatioAllele Frequencyp-value
rs2277311.380.421.0e-08
rs70781601.360.162.0e-08
rs75902681.420.229.0e-08
rs95745651.310.743.0e-07
rs12587631.520.661.0e-06
rs177602961.50.167.0e-06
Simulated Population
ROC PlotGr00375
AUROC0.547631
Logistic Regression Equationlog(p/(1 - p)) = 0.786 - 0.126(rs227731) + 13.922(rs7078160) - 0.238(rs7590268) - 0.112(rs9574565) - 0.387(rs1258763) - 14.490(rs17760296)
Heritability0.009
Regression TypeOLS
Download FileGR00375.csv