Showing GR-Card for GR00363: Multiple sclerosis (HGVRS643)

Record Information
Version1.0
Creation Date2019-04-04 18:01:14 UTC
Last Updated2020-04-06 20:49:12 UTC
GWAS-ROCS IDGR00363
Study Information
Condition/PhenotypeMultiple sclerosis
GWAS Central Data Set IDHGVRS643
PubMed ID19525953
Meta-Analysis (Yes/No)No
Control Subjects9336
Case Subjects4839
SNPs
NameOdds RatioAllele Frequencyp-value
rs25233931.280.591.0e-17
rs18006931.20.452.0e-11
rs23007471.30.883.0e-10
rs174458361.250.814.0e-09
rs178249331.180.254.0e-09
rs21042861.150.769.0e-08
rs8823001.190.611.0e-07
rs68969691.10.622.0e-07
rs118651211.150.692.0e-07
rs17901001.110.247.0e-07
rs12505401.120.352.0e-06
rs68979321.120.752.0e-06
rs41495841.580.0225.0e-06
rs46805341.120.376.0e-06
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Simulated Population
ROC PlotGr00363
AUROC0.563176
Logistic Regression Equationlog(p/(1 - p)) = 1.022 - 1.894(rs2523393) - 0.336(rs1800693) - 0.125(rs2300747) - 0.295(rs17445836) - 0.144(rs17824933) - 0.335(rs2104286) + 1.586(rs882300) + 0.155(rs6896969) + 0.140(rs11865121) - 0.014(rs1790100) + 0.112(rs1250540) + 0.487(rs6897932) - 0.320(rs4149584) + 0.223(rs4680534)
Heritability0.016
Regression TypeOLS
Download FileGR00363.csv