GWAS-ROCS Database: Showing GR-Card for GR00342: Migraine (HGVRS4905)

Record Information

Version

1.0

Creation Date

2019-04-04 18:01:14 UTC

Last Updated

2020-04-06 20:49:11 UTC

GWAS-ROCS ID

GR00342

Study Information

Condition/Phenotype

Migraine

GWAS Central Data Set ID

HGVRS4905

PubMed ID

27322543

Meta-Analysis (Yes/No)

Control Subjects

139622

Case Subjects

8348

SNPs

Name	Odds Ratio	Allele Frequency	p-value
rs11172113	1.11111	0.58	6.0e-49
rs10218452	1.11	0.22	5.0e-38
rs67338227	1.09	0.23	2.0e-27
rs2078371	1.11	0.12	4.0e-24
rs10166942	1.06383	0.8	1.0e-23
rs9349379	1.07527	0.59	6.0e-22
rs1925950	1.07	0.35	9.0e-22
rs4814864	1.07	0.26	2.0e-19
rs1024905	1.06	0.47	2.0e-17
rs186166891	1.09	0.11	1.0e-15
rs10786156	1.05263	0.55	2.0e-14
rs10456100	1.06	0.28	7.0e-13
rs6478241	1.05	0.36	1.0e-12
rs4910165	1.06383	0.67	3.0e-11
rs77505915	1.05	0.45	3.0e-10
rs12260159	1.08696	0.93	3.0e-10
rs12135062	1.05	0.23	4.0e-10
rs17857135	1.06	0.17	5.0e-10
rs4839827	1.05	0.47	6.0e-10
rs11172055	1.04	0.48	1.0e-09
rs13078967	1.14943	0.97	2.0e-09
rs111404218	1.05	0.34	2.0e-09
rs2506142	1.06	0.17	2.0e-09
rs566529	1.06383	0.85	3.0e-09
rs4081947	1.03	0.34	3.0e-09
rs7684253	1.04167	0.55	3.0e-09
rs1268083	1.04167	0.52	5.0e-09
rs75473620	1.12	0.96	6.0e-09
rs75213074	1.1236	0.97	7.0e-09
rs28455731	1.06	0.16	7.0e-09
rs6791480	1.04	0.31	8.0e-09
rs11624776	1.04167	0.69	8.0e-09
rs7544256	1.04167	0.64	9.0e-09
rs144017103	1.17647	0.98	1.0e-08
rs6693567	1.05	0.27	1.0e-08
rs10895275	1.04	0.33	2.0e-08
rs12845494	1.04167	0.73	2.0e-08
rs10155855	1.08	0.05	2.0e-08
rs1572668	1.04	0.48	2.0e-08
rs138556413	1.13636	0.97	2.0e-08
rs561561	1.06383	0.88	3.0e-08
rs2223089	1.07527	0.92	3.0e-08
rs140002913	1.0989	0.94	4.0e-08
rs11031122	1.04	0.24	4.0e-08

show all show less

Simulated Population

ROC Plot

AUROC

0.543216

Logistic Regression Equation

log(p/(1 - p)) = 2.683 - 0.618(rs11172113) - 0.913(rs10218452) - 16.536(rs67338227) - 0.414(rs2078371) - 0.174(rs10166942) - 0.219(rs9349379) - 1.352(rs1925950) - 0.301(rs4814864) - 17.183(rs1024905) + 0.111(rs186166891) + 0.206(rs10786156) + 0.030(rs10456100) + 0.660(rs6478241) - 0.185(rs4910165) + 0.014(rs77505915) - 0.028(rs12260159) + 16.419(rs12135062) + 0.136(rs17857135) + 16.407(rs4839827) - 0.017(rs11172055) + 0.547(rs13078967) - 0.142(rs111404218) - 0.082(rs2506142) - 0.039(rs566529) + 0.777(rs4081947) + 0.215(rs7684253) + 0.027(rs1268083) - 0.044(rs75473620) + 0.001(rs75213074) + 0.136(rs28455731) - 0.148(rs6791480) + 0.225(rs11624776) + 0.344(rs7544256) - 0.112(rs144017103) + 0.192(rs6693567) + 0.179(rs10895275) + 0.065(rs12845494) - 0.092(rs10155855) + 0.795(rs1572668) + 0.031(rs138556413) + 0.171(rs561561) + 0.019(rs2223089) - 0.290(rs140002913) + 0.992(rs11031122)

Heritability

0.007

Regression Type

OLS

Download File

GR00342.csv