Showing GR-Card for GR00300: Late onset Alzheimer's disease (HGVRS1638)

Record Information
Version1.0
Creation Date2019-04-04 18:01:13 UTC
Last Updated2020-04-06 20:49:11 UTC
GWAS-ROCS IDGR00300
Study Information
Condition/PhenotypeLate onset Alzheimer's disease
GWAS Central Data Set IDHGVRS1638
PubMed ID21460841
Meta-Analysis (Yes/No)No
Control Subjects35597
Case Subjects18832
SNPs
NameOdds RatioAllele Frequencyp-value
rs75615281.170.354.0e-14
rs49389331.120.618.0e-12
rs5616551.150.667.0e-11
rs67017131.160.25.0e-10
rs117675571.110.816.0e-10
rs38654441.10.72.0e-09
rs93494071.110.279.0e-09
rs15322781.120.648.0e-08
rs37522461.150.196.0e-07
Simulated Population
ROC PlotGr00300
AUROC0.526675
Logistic Regression Equationlog(p/(1 - p)) = 0.873 - 0.224(rs7561528) - 0.057(rs4938933) - 0.067(rs561655) - 0.158(rs6701713) - 0.065(rs11767557) + 0.032(rs3865444) + 0.176(rs9349407) - 0.030(rs1532278) - 0.107(rs3752246)
Heritability0.003
Regression TypeOLS
Download FileGR00300.csv