Showing GR-Card for GR00269: Immunoglobulin light chain (AL) amyloidosis (HGVRS6410)

Record Information
Version1.0
Creation Date2019-04-04 18:01:13 UTC
Last Updated2020-04-06 20:49:10 UTC
GWAS-ROCS IDGR00269
Study Information
Condition/PhenotypeImmunoglobulin light chain (AL) amyloidosis
GWAS Central Data Set IDHGVRS6410
PubMed ID28025584
Meta-Analysis (Yes/No)No
Control Subjects7526
Case Subjects1229
SNPs
NameOdds RatioAllele Frequencyp-value
rs93441.350.568.0e-11
rs44876451.350.672.0e-09
rs794192691.410.125.0e-08
rs10053001.290.598.0e-08
rs107995991.260.621.0e-06
rs112191221.250.352.0e-06
rs47928001.360.122.0e-06
rs1428026691.30.173.0e-06
rs22731561.290.193.0e-06
rs356298601.260.264.0e-06
Simulated Population
ROC PlotGr00269
AUROC0.55578
Logistic Regression Equationlog(p/(1 - p)) = 2.197 - 0.275(rs9344) - 0.224(rs4487645) - 15.347(rs79419269) + 0.009(rs1005300) + 0.020(rs10799599) - 0.249(rs11219122) + 15.132(rs4792800) - 0.097(rs142802669) + 0.034(rs2273156) + 0.323(rs35629860)
Heritability0.012
Regression TypeOLS
Download FileGR00269.csv