Showing GR-Card for GR00245: Graves disease (HGVRS1723)

Record Information
Version1.0
Creation Date2019-04-04 18:01:12 UTC
Last Updated2020-04-06 20:49:10 UTC
GWAS-ROCS IDGR00245
Study Information
Condition/PhenotypeGraves disease
GWAS Central Data Set IDHGVRS1723
PubMed ID21841780
Meta-Analysis (Yes/No)No
Control Subjects5000
Case Subjects5462
SNPs
NameOdds RatioAllele Frequencyp-value
rs15211.920.792.0e-65
rs22813881.640.322.0e-65
rs49472961.770.144.0e-51
rs64576171.40.457.0e-33
rs121012611.350.647.0e-24
rs10241611.30.692.0e-17
rs68321511.240.351.0e-13
rs37619591.230.42.0e-13
rs93556101.190.477.0e-10
rs3704091.150.672.0e-06
rs5059221.130.538.0e-06
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Simulated Population
ROC PlotGr00245
AUROC0.620031
Logistic Regression Equationlog(p/(1 - p)) = 0.969 - 0.847(rs1521) - 1.988(rs2281388) - 0.632(rs4947296) - 0.910(rs6457617) - 0.330(rs12101261) - 0.973(rs1024161) + 0.129(rs6832151) + 2.251(rs3761959) - 0.121(rs9355610) + 1.045(rs370409) + 0.518(rs505922)
Heritability0.058
Regression TypeOLS
Download FileGR00245.csv