Showing GR-Card for GR00198: Dupuytren's disease (HGVRS4932)

Record Information
Version1.0
Creation Date2019-04-04 18:01:11 UTC
Last Updated2020-04-06 20:49:09 UTC
GWAS-ROCS IDGR00198
Study Information
Condition/PhenotypeDupuytren's disease
GWAS Central Data Set IDHGVRS4932
PubMed ID28886342
Meta-Analysis (Yes/No)No
Control Subjects12937
Case Subjects7912
SNPs
NameOdds RatioAllele Frequencyp-value
rs168797651.8770.1783.0e-81
rs25981071.4770.4472.0e-44
rs6295351.3570.3514.0e-40
rs6117441.29870.5981.0e-32
rs72914121.2880.4132.0e-30
rs29125221.35870.7994.0e-29
rs123421061.290.3084.0e-26
rs389041.2530.4644.0e-23
rs10427041.2590.2482.0e-19
rs61020951.33690.8752.0e-18
rs3945631.207730.5891.0e-17
rs116725171.3410.2842.0e-17
rs10324661.222490.6942.0e-17
rs64965191.264220.8367.0e-17
rs102763031.212120.741.0e-15
rs108668461.190.4212.0e-15
rs75241021.3510.2143.0e-15
rs78387171.1820.4055.0e-14
rs60161421.2770.1321.0e-13
rs23060221.2750.119.0e-11
rs99511091.219510.8671.0e-10
rs174337101.230010.882.0e-10
rs95259271.200480.8332.0e-10
rs15094061.1640.3563.0e-10
rs9779871.1460.4035.0e-10
rs70712751.150.21.0e-06
rs47929011.119820.693.0e-06
rs78661811.1130.3035.0e-06
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Simulated Population
ROC PlotGr00198
AUROC0.703099
Logistic Regression Equationlog(p/(1 - p)) = 0.777 - 18.718(rs16879765) - 17.833(rs2598107) - 1.707(rs629535) - 0.000(rs611744) - 1.482(rs7291412) - 0.428(rs2912522) + 0.115(rs12342106) + 16.938(rs38904) + 2.226(rs1042704) - 17.356(rs6102095) - 0.074(rs394563) - 17.483(rs11672517) - 1.893(rs1032466) + 0.391(rs6496519) - 0.016(rs10276303) + 0.429(rs10866846) + 15.869(rs7524102) + 0.302(rs7838717) + 0.545(rs6016142) - 0.378(rs2306022) - 0.054(rs9951109) + 17.200(rs17433710) - 0.001(rs9525927) + 0.250(rs1509406) + 2.824(rs977987) + 0.362(rs7071275) + 2.126(rs4792901) + 17.160(rs7866181)
Heritability0.165
Regression TypeOLS
Download FileGR00198.csv