Showing GR-Card for GR00180: Crohn's disease (HGVRS2703)

Record Information
Version1.0
Creation Date2019-04-04 18:01:11 UTC
Last Updated2020-04-06 20:49:08 UTC
GWAS-ROCS IDGR00180
Study Information
Condition/PhenotypeCrohn's disease
GWAS Central Data Set IDHGVRS2703
PubMed ID23128233
Meta-Analysis (Yes/No)No
Control Subjects38457
Case Subjects38607
SNPs
NameOdds RatioAllele Frequencyp-value
rs20668473.10.0246.0e-209
rs129949971.230.5234.0e-70
rs92649421.150.3785.0e-28
rs92868791.130.2496.0e-22
rs20240921.160.2158.0e-22
rs37641471.160.2482.0e-21
rs29454121.140.5879.0e-17
rs67167531.130.1961.0e-16
rs66512521.190.8651.0e-16
rs22845531.120.5992.0e-16
rs17289181.120.2995.0e-16
rs5162461.110.4831.0e-15
rs66796771.20.9072.0e-15
rs132047421.170.1248.0e-15
rs2123881.110.413.0e-14
rs131265051.170.0962.0e-12
rs100656371.120.7734.0e-12
rs126633561.10.5334.0e-12
rs38974781.160.8912.0e-11
rs48023071.10.7062.0e-10
rs94916971.080.4394.0e-10
rs77023311.090.6216.0e-10
rs108653311.10.3961.0e-09
rs173916941.130.8893.0e-09
rs169671031.090.2034.0e-09
rs8647451.090.4974.0e-09
rs176950921.10.7035.0e-09
rs70156301.080.7391.0e-08
rs68373351.090.6472.0e-08
rs104864831.090.2473.0e-08
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Simulated Population
ROC PlotGr00180
AUROC0.612408
Logistic Regression Equationlog(p/(1 - p)) = 0.277 - 1.308(rs2066847) - 15.789(rs12994997) - 0.957(rs9264942) + 14.010(rs9286879) - 0.696(rs2024092) - 16.462(rs3764147) - 0.331(rs2945412) - 0.034(rs6716753) - 0.153(rs6651252) - 0.152(rs2284553) + 0.104(rs1728918) - 0.435(rs516246) - 0.166(rs6679677) - 0.085(rs13204742) - 0.417(rs212388) + 0.477(rs13126505) - 0.049(rs10065637) + 15.197(rs12663356) + 0.190(rs3897478) - 0.144(rs4802307) + 0.380(rs9491697) + 0.326(rs7702331) + 1.013(rs10865331) - 0.074(rs17391694) + 0.890(rs16967103) + 0.815(rs864745) - 0.069(rs17695092) + 0.127(rs7015630) + 0.303(rs6837335) + 2.542(rs10486483)
Heritability0.051
Regression TypeOLS
Download FileGR00180.csv