Showing GR-Card for GR00178: Crohn's disease (HGVRS1915)

Record Information
Version1.0
Creation Date2019-04-04 18:01:11 UTC
Last Updated2020-04-06 20:49:08 UTC
GWAS-ROCS IDGR00178
Study Information
Condition/PhenotypeCrohn's disease
GWAS Central Data Set IDHGVRS1915
PubMed ID22412388
Meta-Analysis (Yes/No)No
Control Subjects4381
Case Subjects1708
SNPs
NameOdds RatioAllele Frequencyp-value
rs20767561.660.2461.0e-37
rs112090262.20.9211.0e-18
rs22418801.320.6011.0e-12
rs92927771.370.5972.0e-11
rs92582601.450.1042.0e-10
rs130034641.050.4875.0e-09
rs70761561.190.7517.0e-09
rs65459461.160.777.0e-09
rs112290301.150.3058.0e-09
rs77059241.480.0662.0e-08
rs126776631.150.6592.0e-08
rs107341051.270.3753.0e-08
rs30913161.140.7324.0e-08
rs30913381.230.3284.0e-08
rs115745141.440.0452.0e-07
rs111901411.340.7395.0e-07
rs19064931.190.4323.0e-06
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Simulated Population
ROC PlotGr00178
AUROC0.641743
Logistic Regression Equationlog(p/(1 - p)) = 3.219 + 0.641(rs3091316) - 1.843(rs2076756) - 0.317(rs7705924) + 1.700(rs3091338) - 0.886(rs2241880) - 16.409(rs11190141) + 0.046(rs11229030) + 15.974(rs7076156) - 0.078(rs6545946) - 0.225(rs10734105) + 1.154(rs13003464) - 1.279(rs9292777) + 0.006(rs11574514) + 0.552(rs9258260) - 2.159(rs11209026) + 1.340(rs12677663) - 0.801(rs1906493)
Heritability0.080
Regression TypeOLS
Download FileGR00178.csv