Showing GR-Card for GR00160: Coronary artery disease (HGVRS1451)

Record Information
Version1.0
Creation Date2019-04-04 18:01:10 UTC
Last Updated2020-04-06 20:49:08 UTC
GWAS-ROCS IDGR00160
Study Information
Condition/PhenotypeCoronary artery disease
GWAS Central Data Set IDHGVRS1451
PubMed ID21378990
Meta-Analysis (Yes/No)No
Control Subjects92436
Case Subjects53182
SNPs
NameOdds RatioAllele Frequencyp-value
rs49775741.290.461.0e-22
rs171140361.170.914.0e-19
rs115569241.090.629.0e-18
rs9641841.130.131.0e-17
rs5794591.10.214.0e-14
rs38258071.080.571.0e-12
rs121902871.080.621.0e-12
rs37982201.510.023.0e-11
rs28958111.070.431.0e-10
rs5998391.110.783.0e-10
rs17460481.090.873.0e-10
rs99826011.180.154.0e-10
rs129365871.070.564.0e-10
rs12312061.070.379.0e-10
rs125264531.10.671.0e-09
rs11226081.140.771.0e-09
rs124134091.120.891.0e-09
rs67258871.140.151.0e-09
rs2161721.070.371.0e-09
rs47731441.070.444.0e-09
rs174656371.140.741.0e-08
rs176099401.070.751.0e-08
rs465221.060.532.0e-08
rs23063741.120.183.0e-08
rs112065101.080.829.0e-08
rs78084241.10.121.0e-06
rs76510391.060.542.0e-06
rs49371261.060.695.0e-06
rs31845041.070.446.0e-06
rs109334361.060.497.0e-06
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Simulated Population
ROC PlotGr00160
AUROC0.573513
Logistic Regression Equationlog(p/(1 - p)) = 0.657 - 2.396(rs4977574) - 0.122(rs17114036) - 14.190(rs11556924) - 0.100(rs964184) - 0.076(rs579459) - 0.085(rs3825807) + 14.139(rs12190287) - 0.454(rs3798220) + 0.102(rs2895811) + 0.636(rs599839) + 0.060(rs1746048) - 14.218(rs9982601) - 0.104(rs12936587) + 0.046(rs1231206) + 0.047(rs12526453) - 1.040(rs1122608) + 0.034(rs12413409) + 13.819(rs6725887) - 0.001(rs216172) - 0.127(rs4773144) - 0.261(rs17465637) + 0.388(rs17609940) + 1.231(rs46522) + 0.163(rs2306374) + 0.193(rs11206510) + 0.273(rs7808424) + 0.147(rs7651039) + 0.048(rs4937126) + 1.037(rs3184504) + 0.128(rs10933436)
Heritability0.022
Regression TypeOLS
Download FileGR00160.csv