Showing GR-Card for GR00158: Corneal astigmatism (HGVRS4187)

Record Information
Version1.0
Creation Date2019-04-04 18:01:10 UTC
Last Updated2020-04-06 20:49:08 UTC
GWAS-ROCS IDGR00158
Study Information
Condition/PhenotypeCorneal astigmatism
GWAS Central Data Set IDHGVRS4187
PubMed ID29422769
Meta-Analysis (Yes/No)No
Control Subjects17728
Case Subjects13642
SNPs
NameOdds RatioAllele Frequencyp-value
rs76739841.120.226.0e-09
rs347510921.090.286.0e-07
rs6302031.086960.269.0e-07
rs756072981.140.722.0e-06
rs624011991.150.143.0e-06
rs7539921.09890.713.0e-06
rs32141011.080.684.0e-06
rs109850681.130.126.0e-06
rs99391141.851850.956.0e-06
rs621283791.130.856.0e-06
rs600838761.310.957.0e-06
rs117750371.10.27.0e-06
rs8593621.10.197.0e-06
rs72786711.075270.499.0e-06
rs1421681711.370.099.0e-06
rs70368241.204820.069.0e-06
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Simulated Population
ROC PlotGr00158
AUROC0.549701
Logistic Regression Equationlog(p/(1 - p)) = 1.846 - 0.131(rs7673984) + 0.020(rs34751092) + 0.036(rs630203) - 0.564(rs75607298) + 0.239(rs62401199) + 0.444(rs753992) + 0.040(rs3214101) + 0.187(rs10985068) - 13.412(rs9939114) - 0.046(rs62128379) + 11.928(rs60083876) - 0.048(rs11775037) + 0.127(rs859362) + 0.006(rs7278671) - 0.551(rs142168171) - 0.162(rs7036824)
Heritability0.010
Regression TypeOLS
Download FileGR00158.csv