Showing GR-Card for GR00155: Colorectal cancer (HGVRS6259)

Record Information
Version1.0
Creation Date2019-04-04 18:01:10 UTC
Last Updated2020-04-06 20:49:08 UTC
GWAS-ROCS IDGR00155
Study Information
Condition/PhenotypeColorectal cancer
GWAS Central Data Set IDHGVRS6259
PubMed ID26621817
Meta-Analysis (Yes/No)No
Control Subjects13396
Case Subjects7937
SNPs
NameOdds RatioAllele Frequencyp-value
rs31845041.10.528.0e-09
rs129702911.270.9655.0e-08
rs60510801.120.6491.0e-07
rs20526781.162790.1391.0e-07
rs77407971.120.5132.0e-07
rs110854661.150.7822.0e-07
rs175039191.170.8622.0e-07
rs31812451.120.5142.0e-07
rs762253721.210.9122.0e-07
rs43789541.150.8984.0e-07
rs104576781.10.7734.0e-07
rs170353101.130.8766.0e-07
rs15124361.075270.4471.0e-06
rs111500381.270.9441.0e-06
rs47270121.180.8911.0e-06
rs99012251.110.551.0e-06
rs102175861.075270.4612.0e-06
rs116074991.270.9542.0e-06
rs48168901.111110.3632.0e-06
rs128172111.120.7673.0e-06
rs124465521.086960.2773.0e-06
rs1125418621.30.9624.0e-06
rs344625691.220.9344.0e-06
rs6064601.110.7254.0e-06
rs48530361.086960.2646.0e-06
rs19521571.080.696.0e-06
rs765258801.160.9297.0e-06
rs779229381.176470.0478.0e-06
rs47893781.075270.3529.0e-06
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Simulated Population
ROC PlotGr00155
AUROC0.539713
Logistic Regression Equationlog(p/(1 - p)) = 1.106 + 0.729(rs3184504) + 0.133(rs12970291) - 0.022(rs6051080) - 0.050(rs2052678) - 0.893(rs7740797) - 0.344(rs11085466) - 0.258(rs17503919) - 0.154(rs3181245) - 0.321(rs76225372) + 0.009(rs4378954) + 0.053(rs10457678) + 0.136(rs17035310) + 0.179(rs1512436) - 0.260(rs11150038) - 0.299(rs4727012) - 0.010(rs9901225) + 0.068(rs10217586) + 0.191(rs11607499) - 0.619(rs4816890) + 0.208(rs12817211) - 0.103(rs12446552) - 0.287(rs112541862) - 1.215(rs34462569) - 0.095(rs606460) + 0.005(rs4853036) + 0.187(rs1952157) + 1.687(rs76525880) - 0.158(rs77922938) + 0.589(rs4789378)
Heritability0.006
Regression TypePenalized
Download FileGR00155.csv