GWAS-ROCS Database: Showing GR-Card for GR00114: Celiac disease (HGVRS849)

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Record Information

Version

1.0

Creation Date

2019-04-04 18:01:10 UTC

Last Updated

2020-04-06 20:49:07 UTC

GWAS-ROCS ID

GR00114

Study Information

Condition/Phenotype

Celiac disease

GWAS Central Data Set ID

HGVRS849

PubMed ID

20190752

Meta-Analysis (Yes/No)

Control Subjects

16434

Case Subjects

9451

SNPs

Name	Odds Ratio	Allele Frequency	p-value
rs2187668	6.23	0.26	1.0e-50
rs1464510	1.29	0.49	3.0e-40
rs17810546	1.36	0.13	4.0e-28
rs13151961	1.35	0.86	2.0e-27
rs653178	1.2	0.5	7.0e-21
rs2327832	1.23	0.22	4.0e-19
rs2816316	1.25	0.84	2.0e-17
rs13098911	1.3	0.1	3.0e-17
rs11221332	1.21	0.24	5.0e-16
rs917997	1.19	0.24	1.0e-15
rs1738074	1.16	0.43	3.0e-15
rs802734	1.17	0.31	3.0e-14
rs13003464	1.15	0.4	4.0e-13
rs13010713	1.13	0.45	5.0e-11
rs10903122	1.12	0.52	2.0e-10
rs1893217	1.17	0.17	3.0e-10
rs10806425	1.13	0.4	4.0e-10
rs1250552	1.12	0.53	9.0e-10
rs4819388	1.14	0.72	2.0e-09
rs9792269	1.14	0.76	3.0e-09
rs3748816	1.12	0.66	3.0e-09
rs13314993	1.13	0.46	3.0e-09
rs296547	1.12	0.64	4.0e-09
rs4675374	1.14	0.22	6.0e-09
rs11712165	1.13	0.39	8.0e-09
rs17035378	1.14	0.72	8.0e-09
rs12928822	1.16	0.84	3.0e-08
rs1033180	1.21	0.08	6.0e-08
rs5979785	1.14	0.74	6.0e-08
rs12727642	1.14	0.19	9.0e-08
rs6691768	1.11	0.62	1.0e-07
rs6806528	1.19	0.1	2.0e-07
rs2298428	1.13	0.2	2.0e-07
rs6974491	1.14	0.17	2.0e-07
rs4899260	1.12	0.26	4.0e-07
rs864537	1.1	0.61	4.0e-07
rs10936599	1.12	0.25	5.0e-07
rs2762051	1.13	0.18	7.0e-07
rs2074404	1.11	0.75	1.0e-06
rs859637	1.1	0.49	2.0e-06

show all show less

Simulated Population

ROC Plot

AUROC

0.881337

Logistic Regression Equation

log(p/(1 - p)) = 1.002 - 39.016(rs2187668) - 20.857(rs1464510) - 0.570(rs17810546) - 0.423(rs13151961) - 0.029(rs653178) - 20.267(rs2327832) - 20.503(rs2816316) - 20.033(rs13098911) - 19.604(rs11221332) + 0.193(rs917997) + 0.045(rs1738074) + 0.104(rs802734) - 0.109(rs13003464) + 0.128(rs13010713) - 0.008(rs10903122) - 20.553(rs1893217) + 0.085(rs10806425) + 2.061(rs1250552) - 0.165(rs4819388) + 0.200(rs9792269) + 18.931(rs3748816) - 0.277(rs13314993) - 0.022(rs296547) + 19.982(rs4675374) - 0.002(rs11712165) - 0.081(rs17035378) + 20.406(rs12928822) + 0.096(rs1033180) - 1.074(rs5979785) - 0.121(rs12727642) + 0.028(rs6691768) + 19.934(rs6806528) + 0.555(rs2298428) + 20.082(rs6974491) + 20.547(rs4899260) + 0.007(rs864537) + 18.900(rs10936599) + 0.747(rs2762051) + 1.157(rs2074404) + 18.989(rs859637)

Heritability

0.582

Regression Type

OLS

Download File

GR00114.csv