GWAS-ROCS Database: Showing GR-Card for GR00053: Atrial fibrillation (HGVRS6052)

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Record Information

Version

1.0

Creation Date

2019-04-04 18:01:08 UTC

Last Updated

2020-04-06 20:49:06 UTC

GWAS-ROCS ID

GR00053

Study Information

Condition/Phenotype

Atrial fibrillation

GWAS Central Data Set ID

HGVRS6052

PubMed ID

28416822

Meta-Analysis (Yes/No)

Control Subjects

267395

Case Subjects

27293

SNPs

Name	Odds Ratio	Allele Frequency	p-value
rs2220427	1.707	0.45	2.0e-134
rs6843082	1.842	0.68	1.0e-126
rs2106261	1.326	0.31	1.0e-35
rs3853445	1.33	0.67	2.0e-34
rs60572254	1.43	0.09	3.0e-24
rs2540953	1.094	0.65	3.0e-17
rs7698692	1.129	0.505	8.0e-16
rs12044963	1.11	0.502	4.0e-15
rs883079	1.184	0.42	5.0e-15
rs1049334	1.203	0.71	2.0e-14
rs2296610	1.195	0.125	2.0e-14
rs2047036	1.078	0.257	2.0e-11
rs17461925	1.077	0.797	9.0e-11
rs17059534	1.201	0.081	3.0e-10
rs639652	1.135	0.54	4.0e-09
rs13219206	1.144	0.72	4.0e-08
rs13385	1.094	0.375	2.0e-07
rs1675334	1.087	0.291	6.0e-06
rs4766566	1.11	0.68	7.0e-06

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Simulated Population

ROC Plot

AUROC

0.720987

Logistic Regression Equation

log(p/(1 - p)) = 2.395 - 34.089(rs2220427) - 19.823(rs6843082) - 1.229(rs2106261) - 0.519(rs3853445) - 0.783(rs60572254) + 1.185(rs2540953) + 17.626(rs7698692) - 0.045(rs12044963) + 0.395(rs883079) + 1.969(rs1049334) + 0.617(rs2296610) + 0.048(rs2047036) + 0.183(rs17461925) - 0.236(rs17059534) + 15.513(rs639652) + 16.928(rs13219206) + 1.400(rs13385) + 0.048(rs1675334) + 0.211(rs4766566)

Heritability

0.195

Regression Type

OLS

Download File

GR00053.csv