GWAS-ROCS Database: Showing GR-Card for GR00038: Anti-dsDNA status (HGVRS1460)

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Record Information

Version

1.0

Creation Date

2019-04-04 18:01:08 UTC

Last Updated

2020-04-06 20:49:06 UTC

GWAS-ROCS ID

GR00038

Study Information

Condition/Phenotype

Anti-dsDNA status

GWAS Central Data Set ID

HGVRS1460

PubMed ID

21408207

Meta-Analysis (Yes/No)

Control Subjects

4813

Case Subjects

1717

SNPs

Name	Odds Ratio	Allele Frequency	p-value
rs1150754	2.21	0.13	6.0e-29
rs2187668	2.23	0.12	6.0e-28
rs7574865	1.77	0.23	2.0e-20
rs10488631	1.92	0.11	7.0e-18
rs9888739	1.8	0.13	1.0e-15
rs2736340	1.38	0.23	3.0e-07
rs525410	1.33	0.49	6.0e-07
rs4956211	1.33	0.35	1.0e-06
rs5754217	1.38	0.19	2.0e-06
rs2431697	1.32	0.56	2.0e-06
rs6695567	1.32	0.57	4.0e-06
rs4963128	1.33	0.66	4.0e-06
rs10737562	1.3	0.5	7.0e-06

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Simulated Population

ROC Plot

AUROC

0.701186

Logistic Regression Equation

log(p/(1 - p)) = 1.438 - 34.842(rs1150754) - 2.866(rs2187668) - 1.027(rs7574865) + 1.234(rs10488631) + 18.011(rs9888739) + 0.629(rs2736340) - 1.104(rs525410) + 0.151(rs4956211) + 17.175(rs5754217) - 0.106(rs2431697) - 0.309(rs6695567) - 0.036(rs4963128) + 1.346(rs10737562)

Heritability

0.162

Regression Type

OLS

Download File

GR00038.csv