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Showing GR-Card for GR00035: Amyotrophic lateral sclerosis (HGVRS4529)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:06 UTC
GWAS-ROCS IDGR00035
Study Information
Condition/PhenotypeAmyotrophic lateral sclerosis
GWAS Central Data Set IDHGVRS4529
PubMed ID29566793
Meta-Analysis (Yes/No)No
Control Subjects78454
Case Subjects24965
SNPs
NameOdds RatioAllele Frequencyp-value
rs38499431.190480.23624.0e-30
rs129731921.12360.31954.0e-15
rs750877251.670.00782.0e-14
rs1132479761.390.01497.0e-13
rs746543581.220.04255.0e-09
rs104633111.086960.24794.0e-08
rs99015221.160.06959.0e-08
rs170704921.130.0951.0e-07
rs101391541.080.3391.0e-07
rs101433101.090.24363.0e-07
Simulated Population
ROC PlotGr00035
AUROC0.529818
Logistic Regression Equationlog(p/(1 - p)) = 1.196 - 0.312(rs3849943) - 0.133(rs12973192) - 0.411(rs75087725) - 0.805(rs113247976) - 0.056(rs74654358) + 0.157(rs10463311) + 0.054(rs9901522) - 0.030(rs17070492) + 0.170(rs10139154) - 0.004(rs10143310)
Heritability0.004
Regression TypeOLS
Download FileGR00035.csv