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Showing GR-Card for GR00034: Amyotrophic lateral sclerosis (HGVRS2562)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:06 UTC
GWAS-ROCS IDGR00034
Study Information
Condition/PhenotypeAmyotrophic lateral sclerosis
GWAS Central Data Set IDHGVRS2562
PubMed ID22959728
Meta-Analysis (Yes/No)No
Control Subjects5112
Case Subjects4243
SNPs
NameOdds RatioAllele Frequencyp-value
rs74771.30.483.0e-07
rs38499421.210.234.0e-07
rs80567421.270.115.0e-07
rs110827621.160.367.0e-07
rs19717911.260.471.0e-06
rs49173001.270.462.0e-06
rs95337991.170.364.0e-06
rs45298881.140.435.0e-06
rs13209001.190.347.0e-06
Simulated Population
ROC PlotGr00034
AUROC0.549739
Logistic Regression Equationlog(p/(1 - p)) = 0.443 - 0.402(rs7477) - 0.220(rs3849942) - 0.142(rs8056742) + 0.077(rs11082762) + 0.162(rs1971791) - 0.613(rs4917300) + 0.354(rs9533799) + 0.459(rs4529888) - 0.338(rs1320900)
Heritability0.010
Regression TypeOLS
Download FileGR00034.csv