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Showing GR-Card for GR00030: Alzheimer's disease (HGVRS6397)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:06 UTC
GWAS-ROCS IDGR00030
Study Information
Condition/PhenotypeAlzheimer's disease
GWAS Central Data Set IDHGVRS6397
PubMed ID25778476
Meta-Analysis (Yes/No)No
Control Subjects28667
Case Subjects7902
SNPs
NameOdds RatioAllele Frequencyp-value
rs46631051.190.432.0e-12
rs15827631.149430.632.0e-09
rs27327031.369860.876.0e-09
rs3822161.149430.642.0e-07
rs4764281.162790.812.0e-07
rs111680361.120.53.0e-07
rs1429587191.162790.823.0e-07
rs7583241.162790.814.0e-07
rs104986331.149430.784.0e-07
rs168476091.190.095.0e-07
rs68906951.149430.796.0e-07
rs713808491.470.059.0e-07
rs596167461.29870.851.0e-06
rs22795901.12360.62.0e-06
rs117614411.120.462.0e-06
rs38511791.12360.652.0e-06
rs168301221.170.132.0e-06
rs131467801.230.053.0e-06
rs61109691.20.083.0e-06
rs79207211.120.383.0e-06
rs72074001.136360.755.0e-06
rs1994991.162790.816.0e-06
rs108078281.09890.517.0e-06
rs785380831.320.068.0e-06
rs613106031.190480.848.0e-06
rs22719201.110.398.0e-06
rs750455691.149430.838.0e-06
rs716362131.180.19.0e-06
rs112183431.30.969.0e-06
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Simulated Population
ROC PlotGr00030
AUROC0.532827
Logistic Regression Equationlog(p/(1 - p)) = 1.768 - 0.809(rs4663105) - 0.089(rs1582763) - 0.493(rs2732703) - 0.889(rs382216) + 0.236(rs476428) - 0.048(rs11168036) - 0.195(rs142958719) - 0.132(rs758324) - 0.059(rs10498633) + 0.006(rs16847609) - 0.146(rs6890695) - 13.512(rs71380849) - 0.034(rs59616746) + 0.120(rs2279590) + 0.759(rs11761441) + 0.823(rs3851179) - 0.016(rs16830122) + 11.994(rs13146780) - 0.114(rs6110969) - 0.251(rs7920721) + 0.003(rs7207400) + 0.001(rs199499) + 0.040(rs10807828) + 1.061(rs78538083) - 0.465(rs61310603) + 0.253(rs2271920) + 0.728(rs75045569) - 0.179(rs71636213) + 0.068(rs11218343)
Heritability0.004
Regression TypeOLS
Download FileGR00030.csv