GWAS-ROCS Database: Showing GR-Card for GR00029: Alzheimer's disease (HGVRS6396)

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Record Information

Version

1.0

Creation Date

2019-04-04 18:01:08 UTC

Last Updated

2020-04-06 20:49:06 UTC

GWAS-ROCS ID

GR00029

Study Information

Condition/Phenotype

Alzheimer's disease

GWAS Central Data Set ID

HGVRS6396

PubMed ID

25778476

Meta-Analysis (Yes/No)

Control Subjects

28667

Case Subjects

7902

SNPs

Name	Odds Ratio	Allele Frequency	p-value
rs6733839	1.2	0.41	1.0e-09
rs9331896	1.19048	0.62	3.0e-09
rs679515	1.22	0.21	4.0e-09
rs471470	1.16279	0.68	3.0e-08
rs639012	1.16279	0.7	1.0e-07
rs2854437	1.23457	0.87	2.0e-06
rs17366218	1.53846	0.95	2.0e-06
rs9869689	1.21	0.1	3.0e-06
rs1125355	1.16	0.26	4.0e-06
rs10792832	1.14	0.65	4.0e-06
rs178585	1.13	0.47	4.0e-06
rs721146	1.17	0.21	4.0e-06
rs10018288	1.16	0.19	4.0e-06
rs2876189	1.14	0.31	6.0e-06
rs59406683	1.20482	0.89	6.0e-06
rs1129187	1.13	0.45	7.0e-06
rs71316816	1.25	0.92	9.0e-06

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Simulated Population

ROC Plot

AUROC

0.546305

Logistic Regression Equation

log(p/(1 - p)) = 2.031 - 0.331(rs6733839) - 0.465(rs9331896) - 0.487(rs679515) - 0.145(rs471470) - 0.123(rs639012) - 0.136(rs2854437) + 0.085(rs17366218) - 0.323(rs9869689) + 0.168(rs1125355) + 0.484(rs10792832) + 0.353(rs178585) - 0.059(rs721146) + 0.248(rs10018288) + 0.038(rs2876189) + 0.295(rs59406683) - 0.023(rs1129187) - 0.859(rs71316816)

Heritability

0.009

Regression Type

OLS

Download File

GR00029.csv