Showing GR-Card for GR00026: Alzheimer's disease (HGVRS3769)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:06 UTC
GWAS-ROCS IDGR00026
Study Information
Condition/PhenotypeAlzheimer's disease
GWAS Central Data Set IDHGVRS3769
PubMed ID24162737
Meta-Analysis (Yes/No)No
Control Subjects48466
Case Subjects25580
SNPs
NameOdds RatioAllele Frequencyp-value
rs67338391.220.4097.0e-44
rs107928321.150.6429.0e-26
rs93318961.160.6213.0e-25
rs66564011.180.1976.0e-24
rs9833921.110.5976.0e-16
rs41479291.150.191.0e-15
rs112183431.30.9611.0e-14
rs288349701.10.3667.0e-14
rs117711451.110.6621.0e-13
rs92711921.110.2763.0e-12
rs109483631.10.2665.0e-11
rs14766791.10.7136.0e-10
rs27180581.080.6275.0e-09
rs104986331.10.7836.0e-09
rs171259441.140.0928.0e-09
rs108387251.080.3161.0e-08
rs353496691.080.4883.0e-08
rs1909821.080.5923.0e-08
rs72745811.140.9173.0e-08
rs64487991.080.37.0e-08
rs78183821.070.4698.0e-08
rs23374061.150.8973.0e-07
rs79207211.070.3873.0e-07
rs72952461.070.4063.0e-07
rs80354521.080.6613.0e-07
rs66782751.090.1693.0e-07
rs746151661.290.024.0e-07
rs72251511.10.1214.0e-07
rs93810401.080.7036.0e-07
rs107516671.080.6346.0e-07
rs728073431.350.0167.0e-07
rs38654441.060.6933.0e-06
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Simulated Population
ROC PlotGr00026
AUROC0.590295
Logistic Regression Equationlog(p/(1 - p)) = 1.080 - 1.568(rs6733839) - 1.461(rs10792832) - 14.826(rs9331896) - 0.722(rs6656401) - 0.107(rs983392) + 0.282(rs4147929) - 0.195(rs11218343) - 0.284(rs28834970) - 1.977(rs11771145) - 0.168(rs9271192) - 0.045(rs10948363) - 0.368(rs1476679) + 14.466(rs2718058) + 0.035(rs10498633) - 0.048(rs17125944) + 0.148(rs10838725) + 0.019(rs35349669) - 0.040(rs190982) - 0.110(rs7274581) + 0.217(rs6448799) + 0.776(rs7818382) - 0.102(rs2337406) + 0.830(rs7920721) + 0.161(rs7295246) + 2.282(rs8035452) + 0.332(rs6678275) + 0.078(rs74615166) + 0.084(rs7225151) + 0.098(rs9381040) + 0.994(rs10751667) - 0.242(rs72807343) + 0.808(rs3865444)
Heritability0.033
Regression TypeOLS
Download FileGR00026.csv