Showing GR-Card for GR00016: Age-related macular degeneration (HGVRS3501)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:05 UTC
GWAS-ROCS IDGR00016
Study Information
Condition/PhenotypeAge-related macular degeneration
GWAS Central Data Set IDHGVRS3501
PubMed ID23455636
Meta-Analysis (Yes/No)No
Control Subjects3989
Case Subjects73266
SNPs
NameOdds RatioAllele Frequencyp-value
rs4296081.740.864.0e-89
rs22301991.420.21.0e-41
rs57494821.310.742.0e-26
rs44206381.30.832.0e-20
rs18641631.220.767.0e-16
rs9430801.150.519.0e-16
rs132780621.150.483.0e-15
rs130818551.230.14.0e-13
rs81356651.150.212.0e-11
rs31307831.160.792.0e-11
rs9209151.130.483.0e-11
rs3343531.130.733.0e-11
rs46987751.140.317.0e-11
rs80173041.110.619.0e-11
rs67957351.10.465.0e-09
rs95422361.10.442.0e-08
rs38121111.10.642.0e-08
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Simulated Population
ROC PlotGr00016
AUROC0.554842
Logistic Regression Equationlog(p/(1 - p)) = - 1.939 - 0.741(rs429608) - 0.734(rs2230199) - 1.268(rs5749482) - 0.480(rs4420638) + 1.019(rs1864163) - 0.378(rs943080) - 12.810(rs13278062) + 0.029(rs13081855) + 0.018(rs8135665) + 0.292(rs3130783) + 12.362(rs920915) - 0.058(rs334353) - 0.088(rs4698775) + 0.184(rs8017304) + 0.354(rs6795735) + 0.380(rs9542236) + 0.335(rs3812111)
Heritability0.012
Regression TypeOLS
Download FileGR00016.csv