Showing GR-Card for GR00015: Age-related macular degeneration (HGVRS3076)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:05 UTC
GWAS-ROCS IDGR00015
Study Information
Condition/PhenotypeAge-related macular degeneration
GWAS Central Data Set IDHGVRS3076
PubMed ID23326517
Meta-Analysis (Yes/No)No
Control Subjects19959
Case Subjects4036
SNPs
NameOdds RatioAllele Frequencyp-value
rs37939171.450.24.0e-24
rs68571.230.851.0e-06
rs20756501.230.861.0e-06
rs175868431.180.782.0e-06
rs64809751.210.843.0e-06
rs6213131.150.494.0e-06
rs119860112.50.025.0e-06
rs19676891.180.755.0e-06
rs168515851.30.085.0e-06
rs104061741.240.116.0e-06
rs96460961.350.056.0e-06
rs77503451.160.757.0e-06
rs67216541.260.087.0e-06
rs42931431.180.318.0e-06
rs20496221.150.519.0e-06
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Simulated Population
ROC PlotGr00015
AUROC0.588579
Logistic Regression Equationlog(p/(1 - p)) = 2.063 - 0.403(rs3793917) - 0.162(rs6857) - 0.915(rs2075650) + 0.061(rs17586843) + 0.667(rs6480975) - 0.031(rs621313) - 1.468(rs11986011) - 15.173(rs1967689) - 14.903(rs16851585) + 0.020(rs10406174) + 0.655(rs9646096) + 15.103(rs7750345) + 15.089(rs6721654) - 0.008(rs4293143) + 0.105(rs2049622)
Heritability0.031
Regression TypeOLS
Download FileGR00015.csv