Showing GR-Card for GR00014: Age-related macular degeneration (HGVRS3075)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:05 UTC
GWAS-ROCS IDGR00014
Study Information
Condition/PhenotypeAge-related macular degeneration
GWAS Central Data Set IDHGVRS3075
PubMed ID23326517
Meta-Analysis (Yes/No)No
Control Subjects19959
Case Subjects4036
SNPs
NameOdds RatioAllele Frequencyp-value
rs10611471.40.377.0e-32
rs37939171.390.261.0e-25
rs170502441.280.115.0e-07
rs68571.230.851.0e-06
rs76769991.190.791.0e-06
rs64809751.210.842.0e-06
rs119860112.50.025.0e-06
rs19676891.180.755.0e-06
rs96460961.350.056.0e-06
rs13550231.130.696.0e-06
rs104061741.240.117.0e-06
rs47148881.30.058.0e-06
rs68192661.150.628.0e-06
rs108302281.120.429.0e-06
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Simulated Population
ROC PlotGr00014
AUROC0.574576
Logistic Regression Equationlog(p/(1 - p)) = 1.858 - 0.525(rs1061147) - 0.673(rs3793917) - 14.967(rs17050244) - 0.274(rs6857) - 0.031(rs7676999) + 0.143(rs6480975) - 1.490(rs11986011) - 0.168(rs1967689) + 0.667(rs9646096) + 0.155(rs1355023) + 15.124(rs10406174) + 0.275(rs4714888) + 0.261(rs6819266) + 0.325(rs10830228)
Heritability0.022
Regression TypeOLS
Download FileGR00014.csv