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Showing GR-Card for GR00012: Age-related macular degeneration (HGVRS2370)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:05 UTC
GWAS-ROCS IDGR00012
Study Information
Condition/PhenotypeAge-related macular degeneration
GWAS Central Data Set IDHGVRS2370
PubMed ID22705344
Meta-Analysis (Yes/No)No
Control Subjects19374
Case Subjects6290
SNPs
NameOdds RatioAllele Frequencyp-value
rs10611702.780.3715.0e-67
rs104909242.520.2067.0e-47
rs22301991.830.195.0e-13
rs6411532.130.8992.0e-09
rs28429921.430.2033.0e-07
rs17891101.330.3754.0e-07
rs93327392.630.9551.0e-06
rs7227821.670.8942.0e-06
rs100339001.320.4634.0e-06
Simulated Population
ROC PlotGr00012
AUROC0.75253
Logistic Regression Equationlog(p/(1 - p)) = 3.401 - 18.551(rs1061170) - 2.174(rs10490924) - 18.578(rs2230199) - 1.643(rs641153) + 18.514(rs2842992) + 1.166(rs1789110) - 1.195(rs9332739) + 1.094(rs722782) + 17.808(rs10033900)
Heritability0.255
Regression TypeOLS
Download FileGR00012.csv