Showing GR-Card for GR00011: Age-related macular degeneration (HGVRS2369)

Record Information
Version1.0
Creation Date2019-04-04 18:01:08 UTC
Last Updated2020-04-06 20:49:05 UTC
GWAS-ROCS IDGR00011
Study Information
Condition/PhenotypeAge-related macular degeneration
GWAS Central Data Set IDHGVRS2369
PubMed ID22705344
Meta-Analysis (Yes/No)No
Control Subjects19374
Case Subjects6290
SNPs
NameOdds RatioAllele Frequencyp-value
rs104909243.670.2062.0e-138
rs10611702.780.3711.0e-108
rs6411532.220.8991.0e-17
rs22301991.610.1931.0e-12
rs100339001.310.4636.0e-09
rs93327392.080.9552.0e-08
Simulated Population
ROC PlotGr00011
AUROC0.746263
Logistic Regression Equationlog(p/(1 - p)) = 2.617 - 2.547(rs10490924) - 1.145(rs1061170) - 0.945(rs641153) + 0.782(rs2230199) + 2.015(rs10033900) - 0.342(rs9332739)
Heritability0.243
Regression TypeOLS
Download FileGR00011.csv